Anti -Traf4 Rabbit Polyclonal Primary Antibodies

Anti -TRAF4 Rabbit Polyclonal Primary Antibodies Product Information Application Background The tumor necrosis factor re

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DESCRIPTION

Basic Info

Model NO.	GB111015
Powder	No
Customized	Customized
Certification	GMP, ISO 9001, BP
Suitable for	for Research Only
State	Liquid
Purity	>96%
Model No	GB111015
Size	100UL
Sterilization	Pre-Sterile with Radiation
Concentration	1mg/1ml
Instrument Classification	Class I
Type	Pathological Analysis Equipments
Host Animal	Rabbit
Isotype	Igg
Application	Wb, Ihc, If
Storage	-20ºC
Package	Bottle with Ice, Individual Foil Pouch
Samples	Available
Color	White
Transport Package	Standard Export Carton
Specification	100ul/pc
Trademark	Servicebio
Origin	Wuhan, China
HS Code	3502900000
Production Capacity	50000 Milligram/Milligrams Per Month

Product Description

Anti -TRAF4 Rabbit Polyclonal Primary Antibodies

Product Information

Description	TRAF4 rabbit polyclonal
Protein full name	TNF receptor-associated factor 4
Synonyms	Cysteine-rich motif associated to RING and Traf domains protein 1, Traf4, Cart1, MLN62, tumor necrosis receptor-associated factor 4A
Immunogen	KLH conjugated Synthetic peptide corresponding to Human TRAF4
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus, Cytoplasm
Predicted MW.	53 kDa
Observed MW.	53 kDa
Uniprot ID	Q9BUZ4, Q61382, A8DYU9

Application

Applications	WB	IHC	IF
Species	Human, Mouse, Rat	Mouse, Rat	Mouse, Rat
Dilution	1: 500-1: 1000	1: 250-1: 500	1: 150-1: 250
Positive tissue	thymus, brain, lymph nodes	lymphoid, thymus	lymphoid, thymus

Background

The tumor necrosis factor receptor-associated factor (TRAF) family is a group of signaling adaptors which participate in various signaling pathways through binding of the tumor necrosis factor receptor superfamily. As one of the important member of TRAF family proteins, TRAF4 was initially isolated from breast carcinomas and identified as the first member of the TRAF family to be up-regulated in human carcinomas. TRAF4 is required during embryogenesis in key biological processes including the formation of the trachea, the development of the axial skeleton, and the closure of the neural tube. TRAF4 deficiency leads to severe developmental alterations.

Images

Western blot analysis of TRAF4 (GB111015) at dilution of 1: 1000

Lane 1: Hela cell lysate

Lane 2: Jurkat cell lysate

Lane 3: THP-1 cell lysate

Lane 4: Mouse thymus tissue lysate

Lane 5: Mouse brain tissue lysate

Lane 6: Mouse lymph nodes tissue lysate

Lane 7: Rat thymus tissue lysate

Lane 8: Rat brain tissue lysate

Lane 9: Rat lymph nodes tissue lysate

Immunohistochemistry analysis of paraffin-embedded mouse lymphoid using TRAF4 (GB111015) at dilution of 1: 250

Immunohistochemistry analysis of paraffin-embedded rat thymus using TRAF4 (GB111015) at dilution of 1: 250